Home Therapy Heart and thorax
Home Therapy Heart and thorax

endocarditis - onbekende verwekker

Advices

≥ 18 years

Indications: Endocarditis lenta, Natieve klep - Subacuut begin en langdurig verloop
Priority Medication Remarks
Medication:

benzylpenicilline iv 12million. IU continuous per 24 hours

+

gentamicine iv 3mg/kg 1dd
≥ 18 years

Indications: Acute endocarditis, Natieve klep - Acuut begin en fulminant verloop of intraveneus drugsgebruik
Priority Medication Remarks
Medication:

Flucloxacilline iv 12g continuous per 24 hours

+

gentamicine iv 3mg/kg 1dd
≥ 18 years

Indications: Kunstklependocarditis
Priority Medication Remarks
Medication:

vancomycine iv 1000mg 2dd

+

gentamicine iv 3mg/kg 1dd

General comments

Bij beta-lactam allergie beta-lactam antibioticum vervangen door vancomycine

Vancomycine dosering op geleide van spiegelbeplaing. Streefdalspiegel 15-20 mg/L

Duur van therapie is afhankelijk van verwekker. Overleg met arts-microbioloog. 

Sources

  1. SWAB Guideline VII - Infectieuze endocarditis
    View all guidelines
  2. http://circ.ahajournals.org/content/early/2015/09/15/CIR.0000000000000296.full.pdf+html

    Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications, IDSA richtlijn, 2015

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-291411.2
Updated: 01/11/2016 - 14:46
Status: Published